Novel t(15;19)(q15;p13) chromosome abnormality in a thymic carcinoma.
case_report · Level V
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Abstract
A 22-year-old female with a thymic carcinoma is reported. The tumor was refractory to both chemotherapy and irradiation. The patient died with an aggressive clinical course. Cytogenetic study showed that the tumor cells had a chromosome translocation, t(15;19)(q15;p13), which was not identified previously in human cancer.
Medical subject headings
- Chromosomes, Human, Pair 15
- Chromosomes, Human, Pair 19
- Mediastinal Neoplasms
- Thymus Neoplasms
- Translocation, Genetic