Ubiquitin gets CARDed.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 20403317.
- Also identified by DOI 10.1016/j.cell.2010.03.047.
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Abstract
Ubiquitin-dependent processes are critical for propagating antiviral defense signals during viral infection. In this issue, Zeng et al. (2010) describe how viral RNA and unanchored ubiquitin chains conspire to promote activation of RIG-I and the host cell's antiviral transcriptional program.