How the sequence of a gene can tune its translation.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20403320.
- Also identified by DOI 10.1016/j.cell.2010.03.033 and PMC identifier 2866089.
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Abstract
Sixty-one codons specify 20 amino acids, offering cells many options for encoding a polypeptide sequence. Two new studies (Cannarrozzi et al., 2010; Tuller et al., 2010) now foster the idea that patterns of codon usage can control ribosome speed, fine-tuning translation to increase the efficiency of protein synthesis.
Medical subject headings
- Codon
- Protein Biosynthesis
- Ribosomes