Imaging breast cancer chemotherapy response with light. Commentary on Soliman et al., p. 2605.

Tromberg, Bruce J; Cerussi, Albert E · Clin Cancer Res · 2010

editorial · Level V

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Abstract

Diffuse optical spectroscopy (DOS), which is used to image tumor metabolic response to neoadjuvant chemotherapy (NAC), shows large changes in tumor functional parameters with significant reductions in oxy- and deoxyhemoglobin for responders versus nonresponders. Although investigational, DOS may provide a cost-effective, risk-free method for optimizing NAC drug and dosing strategies for individual patients.

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