Two different microtubule-based motor activities with opposite polarities in kinetochores.

Hyman, A A; Mitchison, T J · Nature · 1991

basic_science · Level V

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Abstract

The movement of microtubules on the kinetochores of isolated chromosomes has been examined by video microscopy. Two different microtubule-based motors on the kinetochore were identified, which have opposite directions of movement. The activities of these two motors can be regulated by factors that can influence phosphorylation.

Medical subject headings