Ironing out the phosphorus problem.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20431575.
- Also identified by DOI 10.1038/ki.2009.560.
- No licence information is recorded for this record.
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Abstract
Control of serum phosphorus remains a vexing problem in chronic kidney disease. Although novel dialysis regimens may provide excellent phosphorus control, phosphate binders remain necessary for most dialysis patients. Block et al. present a phase I clinical trial examining the safety and efficacy of SBR759, a novel non-calcium, iron-based phosphate binder. Although the risks of iron accumulation and hypocalcemia must be addressed, this phosphate binder appears to be well tolerated and effective and offers a powder-based formulation.
Medical subject headings
- Kidney Failure, Chronic
- Phosphorus