Regulation of RNA polymerase II elongation by c-Myc.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20434979.
- Also identified by DOI 10.1016/j.cell.2010.04.016.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The genome-wide mapping presented in this issue by Rahl et al. (2010) demonstrates how the transcription factor c-Myc interfaces with the machinery that controls RNA polymerase II elongation. These findings account for the ability of c-Myc to activate the expression of a large number of genes that promote rapid proliferation.