Group-based psychosocial intervention for bipolar disorder: randomised controlled trial.

Castle, David; White, Carolynne; Chamberlain, James; Berk, Michael; Berk, Lesley; Lauder, Sue; Murray, Greg; Schweitzer, Isaac et al. · Br J Psychiatry · 2010

rct · Level II

Where this comes from

Abstract

Psychosocial interventions have the potential to enhance relapse prevention in bipolar disorder. To evaluate a manualised group-based intervention for people with bipolar disorder in a naturalistic setting. Eighty-four participants were randomised to receive the group-based intervention (a 12-week programme plus three booster sessions) or treatment as usual, and followed up with monthly telephone interviews (for 9 months post-intervention) and face-to-face interviews (at baseline, 3 months and 12 months). Participants who received the group-based intervention were significantly less likely to have a relapse of any type and spent less time unwell. There was a reduced rate of relapse in the treatment group for pooled relapses of any type (hazard ratio 0.43, 95% CI 0.20-0.95; t(343) = -2.09, P = 0.04). This study suggests that the group-based intervention reduces relapse risk in bipolar disorder.

Medical subject headings