Auditory hallucinations and brain structure in schizophrenia: voxel-based morphometric study.

Nenadic, Igor; Smesny, Stefan; Schlösser, Ralf G M; Sauer, Heinrich; Gaser, Christian · Br J Psychiatry · 2010

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Abstract

We applied voxel-based morphometry to high-resolution magnetic resonance images of 99 participants with schizophrenia. Voxel-wise correlations with a score of auditory hallucination severity identified areas in the left and right superior temporal cortex (including Heschl's gyrus), left supramarginal/angular gyrus, left postcentral gyrus and left posterior cingulate cortex. This study extends previous region-of-interest studies demonstrating main effects of auditory hallucinations related to modality-specific superior temporal areas including primary and secondary auditory cortices.

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