Administration of ondansetron is associated with lethal outcome.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 20439600.
- Also identified by DOI 10.1542/peds.2009-2795.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We report here the case of a child with a known muscular abnormality and susceptibility to malignant hyperthermia who abruptly died after receiving a therapeutic dose of ondansetron. Also, we discuss the pharmacodynamic relationship of ondansetron to malignant hyperthermia in a susceptible host.
Medical subject headings
- Antiemetics
- Genetic Predisposition to Disease
- Malignant Hyperthermia
- Myopathies, Structural, Congenital
- Ondansetron
- Ryanodine Receptor Calcium Release Channel