Lysosomal Rag-ulation of mTOR complex 1 activity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20444413.
- Also identified by DOI 10.1016/j.cmet.2010.04.010.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
An amino acid-sensing pathway regulates mTOR complex 1 (mTORC1) activity and participates in nutrient control of cell metabolism and growth. Sancak et al. (2010) identify a lysosomal membrane-localized super-complex that drives amino acid-dependent mTORC1 activation.