Intestinal ecology in the metabolic syndrome.
basic_science · Level V
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- Record sourced from PubMed, PMID 20444415.
- Also identified by DOI 10.1016/j.cmet.2010.04.012.
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Abstract
Nutritional and genetic factors alter the intestinal microflora, predisposing individuals toward metabolic syndrome. Gewirtz and coworkers (Vijay-Kumar et al., 2010), employing Toll-like receptor 5 null mice, present evidence for a direct relationship between malfunction of the innate immune system, changes in gut microbiota composition, and development of metabolic syndrome.