Gastric acid secretion and parietal cell mass: effect of sex hormones.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 2044927.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The role of sex hormones on parietal cell function and number was studied in the rat. Ovariectomy significantly increased parietal cell mass (from 18.26 +/- 0.16 x 10(6) to 24.14 +/- 0.89 x 10(6] as well as basal acid secretion (from 3.49 +/- 0.06 to 3.63 +/- 0.05 mu Eq/10 min). Castration decreased the number of parietal cells in the gastric mucosa of male rats from 25.57 +/- 0.18 x 10(6) to 18.65 +/- 0.12 x 10(6) and basal acid secretion (from 3.99 +/- 0.03 to 3.50 +/- 0.06 mu Eq/10 min). The results suggest that male and female sex hormones regulate basal acid secretion via their effects on the parietal cell.
Medical subject headings
- Cell Count
- Gastric Acid
- Gonadal Steroid Hormones
- Parietal Cells, Gastric