Insightful tales from single embryonic cells.

Marks, Hendrik; Veenstra, Gert Jan C; Stunnenberg, Hendrik G · Cell Stem Cell · 2010

basic_science · Level V

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Abstract

Two studies by Guo et al. (2010) and Tang et al. (2010) use comprehensive and systematic single-cell RNA profiling to address pivotal questions in mouse embryonic biology: when initial asymmetries become apparent during development and how cells adapt to an in vitro environment to become embryonic stem cells.