Emergence of cytomegalovirus disease in patients receiving temozolomide: report of two cases and literature review.
case_series · Level IV
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- Record sourced from PubMed, PMID 20455691.
- Also identified by DOI 10.1086/653011.
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Abstract
Temozolomide chemotherapy has become part of the therapy used to treat glioblastoma multiforme and refractory anaplastic astrocytoma. Temozolomide frequently produces profound lymphopenia. We report 2 cases of cytomegalovirus disease that occurred in patients receiving temozolomide therapy and review 4 additional cases reported in the literature. Narrow monitoring with cytomegalovirus antigenemia assay should be considered for recommendation.
Medical subject headings
- Antineoplastic Agents, Alkylating
- Cytomegalovirus Infections
- Dacarbazine