Next-generation biomarkers for detecting kidney toxicity.

Bonventre, Joseph V; Vaidya, Vishal S; Schmouder, Robert; Feig, Peter; Dieterle, Frank · Nat Biotechnol · 2010

review · Level V

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Abstract

There is a paucity of biomarkers that reliably detect nephrotoxicity. The Predictive Safety Testing Consortium (PSTC) faced several challenges in identifying novel safety biomarkers in the renal setting.

Medical subject headings