Synthesis and characterization of gold at gold(i)-thiomalate core at shell nanoparticles.

Corthey, Gastón; Giovanetti, Lisandro J; Ramallo-López, José M; Zelaya, Eugenia; Rubert, Aldo A; Benitez, Guillermo A; Requejo, Félix G; Fonticelli, Mariano H et al. · ACS Nano · 2010

basic_science · Level V

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Abstract

In this paper, the synthesis of gold at gold(I)-thiolate core at shell nanoparticles is described for the first time. The chemical nature and structure of these nanoparticles were characterized by a multi-technique approach. The prepared particles consist of gold metallic cores, about 1 nm in size, surrounded by stable gold(I)-thiomalate shells (Au at Au(I)-TM). These nanoparticles could be useful in medicine due to the interesting properties that gold(I)-thiomalate has against rheumatoid arthritis. Furthermore, the described results give new insights in the synthesis and characterization of metallic and core at shell nanoparticles.

Medical subject headings