Epigenetic markers in rectal cancer.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20460492.
- Also identified by DOI 10.1158/1078-0432.CCR-10-0559.
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Abstract
DNA methylation changes in rectal cancer may serve as a new screening marker and a tool for monitoring recurrence. Importantly, these changes may also function as a predictive marker to allow appropriate exclusion of (neo)adjuvant therapies in patients at low risk for disease recurrence, sparing them from potential treatment-related morbidities.
Medical subject headings
- Biomarkers, Tumor
- DNA Methylation
- Epigenesis, Genetic
- Rectal Neoplasms