Not all autophagy membranes are created equal.

McEwan, David G; Dikic, Ivan · Cell · 2010

basic_science · Level V

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Abstract

During starvation, the cell recycles cytoplasmic material by sequestering it in double-membrane organelles, called autophagosomes, which eventually fuse with lysosomes. In this issue, Hailey et al. (2010) identify the outer membrane of mitochondria as a new source of autophagosomal membranes during starvation.