Rong's numbers: accelerating progress in HCV therapeutic research.
Where this comes from
- Record sourced from PubMed, PMID 20505213.
- Also identified by DOI 10.1126/scitranslmed.3001183.
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Abstract
Rong and colleagues have applied a mathematical model of hepatitis C virus (HCV) replication to experimental data from initial clinical investigations of HCV protease inhibitors. In this Perspective, we discuss how mathematical modeling and other modern translational research tools and approaches can be used to expedite drug development with well-designed combination clinical trials that test drugs from multiple collaborators.
Medical subject headings
- Hepacivirus
- Hepatitis C
- Protease Inhibitors