Wrapping up stereocilia rootlets.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20510920.
- Also identified by DOI 10.1016/j.cell.2010.05.022.
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Abstract
The actin-filled stereocilia of cochlear hair cells deflect in response to sound by pivoting around rootlets at their insertion points at the sensory cell surface. Kitajiri et al. (2010) now show that the actin-binding protein TRIOBP tightly bundles the actin filaments into rootlets, endowing these stereocilia "pivots" with unique elasticity and robustness.