For synapses, it's depression not death.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 20510921.
- Also identified by DOI 10.1016/j.cell.2010.05.013.
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Abstract
Long-term depression (LTD) of synaptic strength is an activity-dependent process in neurons that may be important for learning and memory. Li et al. (2010) now reveal a new apoptosis-independent role for mitochondrial-activated caspases in LTD suggesting that neurons have co-opted the canonical cell death pathway to perform a specialized function at synapses.