Viral houseguests undertake interior redesign.
basic_science · Level V
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- Record sourced from PubMed, PMID 20510923.
- Also identified by DOI 10.1016/j.cell.2010.05.012 and PMC identifier 9880789.
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Abstract
As part of their life cycle some single-stranded RNA viruses remodel host cytoplasmic membranes into specialized organelles. In this issue, Hsu et al. (2010) demonstrate how the viruses selectively co-opt host machinery to make this unique organelle, which has a lipid composition favorable to viral replication.