Imaging atherosclerotic plaque inflammation by fluorodeoxyglucose with positron emission tomography: ready for prime time?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20513592.
- Also identified by DOI 10.1016/j.jacc.2009.12.061.
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Abstract
Inflammation is a determinant of atherosclerotic plaque rupture, the event leading to most myocardial infarctions and strokes. Although conventional imaging techniques identify the site and severity of luminal stenosis, the inflammatory status of the plaque is not addressed. Positron emission tomography imaging of atherosclerosis using the metabolic marker fluorodeoxyglucose allows quantification of arterial inflammation across multiple vessels. This review sets out the background and current and potential future applications of this emerging biomarker of cardiovascular risk, along with its limitations.
Medical subject headings
- Atherosclerosis
- Coronary Artery Disease
- Fluorodeoxyglucose F18
- Image Processing, Computer-Assisted
- Inflammation
- Positron-Emission Tomography