Autophagy: a potential link between obesity and insulin resistance.
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- Record sourced from PubMed, PMID 20519116.
- Also identified by DOI 10.1016/j.cmet.2010.05.006.
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Abstract
Dysregulation of autophagy contributes to aging and to diseases such as neurodegeneration, cardiomyopathy, and cancer. The paper by Yang et al. (2010) in this issue of Cell Metabolism indicates that defective autophagy may also underlie impaired insulin sensitivity in obesity and that upregulating autophagy can combat insulin resistance.