L-tryptophan supplementation does not affect postoperative pain intensity or consumption of analgesics.
Where this comes from
- Record sourced from PubMed, PMID 2052393.
- Also identified by DOI 10.1016/0304-3959(91)90093-D.
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Abstract
Aiming at optimizing serotonin levels in endogenous pain-modulating systems, L-tryptophan supplementation pre- and postoperatively (2 g/day for 7 days) did not affect pain development or analgesic consumption after third molar surgery. Biological effects related to an increase in mood were observed, however, indicating transport of L-tryptophan to the central nervous system. The findings are discussed in relation to earlier reports on favorable effects of L-tryptophan on experimental pain in healthy subjects and in chronic pain patients.
Medical subject headings
- Analgesics
- Postoperative Pain
- Tryptophan