Palivizumab-resistant human respiratory syncytial virus infection in infancy.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 20528472.
- Also identified by DOI 10.1086/653534.
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Abstract
Palivizumab-resistant respiratory syncytial virus was isolated from an infant treated with palivizumab. A stable mutation at codon 276 led to a nearly complete resistance to palivizumab. Additional studies revealed a second mutation at codon 272. Further passage of the virus led to a complete loss of binding of palivizumab.
Medical subject headings
- Antibodies, Monoclonal
- Antiviral Agents
- Drug Resistance, Viral
- Respiratory Syncytial Virus Infections
- Respiratory Syncytial Virus, Human