High prevalence of macrolide resistance in Mycoplasma pneumoniae isolates from adult and adolescent patients with respiratory tract infection in China.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 20540621.
- Also identified by DOI 10.1086/653535.
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Abstract
The resistance rate of 67 Mycoplasma pneumoniae isolates from 356 ambulatory adult patients with respiratory tract infection was 69% (46 of 67). All 46 macrolide-resistant strains harbored point mutations in the 23S ribosomal RNA gene. Patients infected with macrolide-resistant M. pneumoniae required significantly longer durations of antibiotic therapy and had longer time to resolution of fever.
Medical subject headings
- Anti-Bacterial Agents
- Drug Resistance, Bacterial
- Macrolides
- Mycoplasma pneumoniae
- Pneumonia, Mycoplasma