ATM Creates a veil of transcriptional silence.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20550929.
- Also identified by DOI 10.1016/j.cell.2010.05.035.
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Abstract
The ATM kinase orchestrates diverse responses to DNA damage. By simultaneously monitoring transcription and DNA-damage responses in single cells, Shanbhag et al. (2010) now uncover a role of ATM in preventing transcription near DNA double-strand breaks.