The quest for the elusive causative SNP.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20551924.
- Also identified by DOI 10.1038/ki.2010.96.
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Abstract
El Kares et al. present evidence that fetal genetic variation in the 3' end of ALDH1A2 may influence nephrogenesis and blood retinoic acid levels. This may be correct, but only replication of this association, ideally accounting for both the fetal and the maternal genotypes, will provide a better understanding of the biology that underlies the association.
Medical subject headings
- Polymorphism, Single Nucleotide