Takayasu arteritis in children and adolescents.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20562196.
- Also identified by DOI 10.1093/rheumatology/keq167.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Takayasu arteritis is a devastating vasculitis of the aorta and its major branches. The clinical manifestations in paediatric patients are less specific than in adults: in children the disease presents with fever, arthralgias and hypertension. Intramural inflammation results in narrowing of the blood vessel lumen and therefore hypoperfusion of the parenchyma. Conventional angiography is the gold standard diagnostic procedure. Corticosteroids, cyclophosphamide, MTX and biological therapies such as TNF-α blocking agents are treatment options.
Medical subject headings
- Adrenal Cortex Hormones
- Antirheumatic Agents
- Cyclophosphamide
- Takayasu Arteritis
- Tumor Necrosis Factor-alpha