Rationale and practical techniques for mouse models of early vein graft adaptations.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20573477.
- Also identified by DOI 10.1016/j.jvs.2010.03.048 and PMC identifier 2912980.
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Abstract
Mouse models serve as relatively new yet powerful research tools to study intimal hyperplasia and wall remodeling of vein bypass graft failure. Several model variations have been reported in the past decade. However, the approach demands thoughtful preparation, selected sophisticated equipment, microsurgical technical expertise, advanced tissue processing, and data acquisition. This review compares several described models and aims (building on our personal experiences) to practically aid the investigators who want to utilize mouse models of vein graft failure.
Medical subject headings
- Graft Survival
- Vascular Surgical Procedures
- Veins