DNA repair: How to accurately bypass damage.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20577203.
- Also identified by DOI 10.1038/4651023a and PMC identifier PMC2717799.
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Abstract
Ultraviolet radiation can cause cancer through DNA damage — specifically, by linking adjacent thymine bases. Crystal structures show how the enzyme DNA polymerase η accurately bypasses such lesions, offering protection.