Serologic assays specific to immunoglobulin M antibodies against hepatitis E virus: pangenotypic evaluation of performances.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 20578874.
- Also identified by DOI 10.1086/654801.
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Abstract
Six immunoassays for detecting immunoglobulin M antibodies to hepatitis E virus were evaluated. Serum samples representing acute infection by each of the 4 viral genotypes as well as nonacute hepatitis E virus infection constituted the test panels. Diagnostic sensitivities and specificities as well as interassay agreement varied widely. Analytical sensitivity limits also were determined and were found to be particularly disparate.
Medical subject headings
- Hepatitis Antibodies
- Hepatitis E
- Hepatitis E virus
- Immunoglobulin M
- Virology