Conjugated oligoelectrolyte harnessed polyhedral oligomeric silsesquioxane as light-up hybrid nanodot for two-photon fluorescence imaging of cellular nucleus.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20589775.
- Also identified by DOI 10.1002/adma.201001544.
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Abstract
A water-soluble organic/inorganic hybrid nanodot based on polyhedral oligomeric silsesquioxane (POSS) and conjugated oligoelectrolyte is designed and synthesized for two-photon fluorescence imaging of cellular nucleus, which takes advantage of its small size (∼3.3 nm) that imparts nucleus permeability and substantial DNA-enhanced two-photon excited fluorescence that allows illuminating the nucleus with a high contrast.
Medical subject headings
- Cell Nucleus
- Organosilicon Compounds
- Photons
- Quantum Dots