Retrotransposition and structural variation in the human genome.
review · Level V
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- Record sourced from PubMed, PMID 20602993.
- Also identified by DOI 10.1016/j.cell.2010.06.014.
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Abstract
New assays are revealing that the diploid human genome contains extensive amounts of structural variation. Genome-wide approaches described in three papers in this issue (Beck et al., 2010; Huang et al., 2010; Iskow et al., 2010) paint a dynamic portrait of our genome, revealing a prominent role for repetitive sequences in shaping its structural variation.