Copy coats: COPI mimics clathrin and COPII.
basic_science · Level V
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- Record sourced from PubMed, PMID 20603010.
- Also identified by DOI 10.1016/j.cell.2010.06.031.
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Abstract
The assembly of COPI into a cage-like lattice sculpts membrane vesicles that transport cargo from the Golgi apparatus. Now, Lee and Goldberg (2010) present X-ray crystal structures of COPI suggesting that these coats combine selected features of two other archetypal coats, clathrin and COPII.