TGF-beta receptors PAR-ticipate in axon formation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20603011.
- Also identified by DOI 10.1016/j.cell.2010.06.024.
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Abstract
How does a newborn neuron initiate and elaborate an axon? Using cutting-edge approaches, Yi et al. (2010) provide striking evidence that TGF-beta signaling via the Par polarity complex is required for axon formation by neocortical pyramidal neurons.