Coronary vasospasm secondary to labetalol in a patient with aortic dissection.

Sandler, M A; Jacobs, L E; Kotler, M N · Chest · 1991

case_report · Level V

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Abstract

A 66-year-old hypertensive woman presented with epigastric and scapular pain on the basis of type 3 aortic dissection. Appropriate therapy with a combined alpha-adrenergic and beta-adrenergic antagonist agent prevented further ongoing dissection and amelioration of symptoms. On day 5, an episode of coronary vasospasm occurred presumably due to beta-blockade with unopposed alpha-adrenergic activity.

Medical subject headings