Cloud-Coffee: implementation of a parallel consistency-based multiple alignment algorithm in the T-Coffee package and its benchmarking on the Amazon Elastic-Cloud.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 20605929.
- Also identified by DOI 10.1093/bioinformatics/btq304 and PMC identifier 2905555.
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Abstract
We present the first parallel implementation of the T-Coffee consistency-based multiple aligner. We benchmark it on the Amazon Elastic Cloud (EC2) and show that the parallelization procedure is reasonably effective. We also conclude that for a web server with moderate usage (10K hits/month) the cloud provides a cost-effective alternative to in-house deployment. T-Coffee is a freeware open source package available from http://www.tcoffee.org/homepage.html
Medical subject headings
- Algorithms
- Sequence Alignment
- Software