Management of protamine allergy with bivalirudin during coronary artery revascularization.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 20609794.
- Also identified by DOI 10.1016/j.athoracsur.2010.01.076.
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Abstract
A patient with impaired left ventricular function was scheduled for coronary artery bypass grafting. The patient's history revealed a life-threatening allergy to fish proteins. Therefore, because of the threat of cross-reactivity to protamine, a standard anticoagulation protocol with heparin/protamine was disapproved. Instead, complete coronary artery revascularization was successfully performed off-pump using bivalirudin as the anticoagulant.
Medical subject headings
- Anticoagulants
- Coronary Artery Disease
- Drug Hypersensitivity
- Heparin Antagonists
- Peptide Fragments
- Protamines