Visceral involvements and long-term sequelae in drug-induced hypersensitivity syndrome.

Kano, Yoko; Ishida, Tadashi; Hirahara, Kazuhisa; Shiohara, Tetsuo · Med Clin North Am · 2010

review · Level V

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Abstract

Drug-induced hypersensitivity syndrome (DIHS) is a severe systemic reaction with several herpesvirus reactivations. Multiple organ failures appear during the course of the disease. The severity of DIHS is determined by the degree of visceral involvement. Autoimmune diseases also develop several months to years after the apparent clinical resolution of DIHS.

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