Perioperative anaphylaxis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20609862.
- Also identified by DOI 10.1016/j.mcna.2010.04.002.
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Abstract
The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents are most frequently incriminated, followed by latex and antibiotics, although any drug or substance used may be a culprit. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests, specific immunoglobulin E, or basophil activation assays. Treatment consists of rapid volume expansion and epinephrine administration titrated to symptom severity.
Medical subject headings
- Anaphylaxis
- Anesthesia
- Anti-Bacterial Agents
- Intraoperative Complications
- Latex
- Neuromuscular Blocking Agents