Identification of a cellulose synthase-associated protein required for cellulose biosynthesis.
basic_science · Level V
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- Record sourced from PubMed, PMID 20616083.
- Also identified by DOI 10.1073/pnas.1007092107 and PMC identifier 2919928.
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Abstract
Cellulose synthase-interactive protein 1 (CSI1) was identified in a two-hybrid screen for proteins that interact with cellulose synthase (CESA) isoforms involved in primary plant cell wall synthesis. CSI1 encodes a 2,150-amino acid protein that contains 10 predicted Armadillo repeats and a C2 domain. Mutations in CSI1 cause defective cell elongation in hypocotyls and roots and reduce cellulose content. CSI1 is associated with CESA complexes, and csi1 mutants affect the distribution and movement of CESA complexes in the plasma membrane.
Medical subject headings
- Arabidopsis
- Arabidopsis Proteins
- Carrier Proteins
- Cellulose
- Glucosyltransferases