Real-time, step-wise, electrical detection of protein molecules using dielectrophoretically aligned SWNT-film FET aptasensors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20617261.
- Also identified by DOI 10.1039/c005276k.
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Abstract
Aptamer functionalized addressable SWNT-film arrays between cantilever electrodes were successfully developed for biosensor applications. Dielectrophoretically aligned SWNT suspended films made possible highly specific and rapid detection of target proteins with a large binding surface area. Thrombin aptamer immobilized SWNT-film FET biosensor resulted in a real-time, label-free, and electrical detection of thrombin molecules down to a concentration of ca. 7 pM with a step-wise rapid response time of several seconds.
Medical subject headings
- Aptamers, Nucleotide
- Biosensing Techniques
- Electrophoresis
- Nanotubes
- Proteins