GPIHBP1: lipoprotein lipase's ticket to ride.
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- Record sourced from PubMed, PMID 20620987.
- Also identified by DOI 10.1016/j.cmet.2010.06.005.
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Abstract
The mechanism of lipoprotein lipase (LPL) transport from muscle and fat cells to the luminal (apical) surface of capillaries, where it hydrolyses lipoprotein triglycerides, has remained undefined. In this issue, Davies et al. (2010) report that GPIHBP1 is required for LPL transcytosis from the basolateral to apical capillary endothelial surface.