Insulin release: shedding light on a complex matter.
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- Record sourced from PubMed, PMID 20620989.
- Also identified by DOI 10.1016/j.cmet.2010.06.002.
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Abstract
SNAP25 and syntaxin-1 are core proteins of the exocytosis machinery for insulin granules. Takahashi et al. (2010) show that the distribution and kinetics of the SNAP25/syntaxin-1 complex assembly play a key role in regulating the first and second phase of insulin release.