Tumor oncogenotypes and lung cancer stem cell identity.
basic_science · Level V
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- Record sourced from PubMed, PMID 20621039.
- Also identified by DOI 10.1016/j.stem.2010.06.005 and PMC identifier 3374716.
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Abstract
In this issue of Cell Stem Cell, Curtis et. al. (2010) reveal that the identities of lung cancer stem cell populations differ depending on the specific tumor oncogenotype in three murine lung adenocarcinoma models. These findings highlight the importance of determining the cancer stem cell oncogenotype for genotypically diverse malignancies.