When fibroblasts MET iPSCs.
editorial · Level V
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- Record sourced from PubMed, PMID 20621040.
- Also identified by DOI 10.1016/j.stem.2010.05.018.
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Abstract
Two independent studies by Li et al. (2010) and Samavarchi-Tehrani et al. (2010) in this issue of Cell Stem Cell suggest that a mesenchymal-to-epithelial transition is a critical initiating event during the derivation of induced pluripotent stem cells (iPSCs) from fibroblasts, indicating remarkable similarities between cellular reprogramming, development, and cancer.