Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs.
basic_science · Level V
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- Record sourced from PubMed, PMID 20621041.
- Also identified by DOI 10.1016/j.stem.2010.06.008.
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Abstract
Recently in Nature Biotechnology, Rodin et al. (2010), Melkoumian et al. (2010), and Villa-Diaz et al. (2010) described defined, nonxenogenic substrates that support long-term self-renewal of human embryonic stem cells (hESCs). Used in conjunction with defined media, these substrates will facilitate expansion of hESCs for therapeutic applications.